Hemolytic Uremic Syndrome
نویسندگان
چکیده
In1955 Gaser et al first reported Hemolytic uremic syndrome (HUS) in children who showed microangiopathic haemolytic anemia, thrombocytopenia, and acute renal failure [1]. HUS, recognised for more than 55 years, is one of the most common causes of acute renal failure in children [2]. It consists of the triad of microangiopathic haemolytic anemia, thrombocytopenia, and acute renal failure. The syndrome usually occurs in previously healthy children and often is preceded by an attack of diarrhoea or dysentery. HUS has several features which are common to thrombotic thrombocytopenic purpura (TTP). They share a common underlying pathologic process termed thrombotic microangiopathy (TMA), characterized by endothelial cell injury, intravascular plateletfibrin thrombi, and vascular damage [3].
منابع مشابه
Concurrent Atypical Hemolytic Uremic Syndrome and Autoimmune Hemolytic Anemia: a case report
Background: Atypical hemolytic uremic syndrome (aHUS) is a life-threatening and scarce disorder characterized by acute renal failure and disease, non-immune microangiopathic hemolytic anemia and thrombocytopenia, leading to end-stage renal failure or death, and consequently maybe accompanying by extra renal manifestations. Case report: We reported aHUS accompanied by autoimmune hemolytic anemi...
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Background and objective: Hemolytic uremic syndrome (HUS) is the most prevalent cause of children renal insufficiency which in many cases (90%) occurs following diarrhea. Hemolytic microangiopathic anemia, thrombocytopenia, and renal insufficiency are main symptoms of hemolytic uremic syndrome. This stud...
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Background and Objective: Hemolytic Uremic Syndrome (HUS) is a thrombotic microangiopathy that contains hemolytic anemia, thrombocytopenia, renal failure and other organ involvement including central nervous system. Frequency of neurologic complications in patients with HUS is high and important cause of mortality. This study was performed to determine seizure disorders in term of acute neurolo...
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The purpose of this study has been to evaluate various factors influencing prognosis in children with hemolytic-uremic syndrome (HUS). Forty children with classical picture of HUS were seen in 1986-1 991. Boys and girls were equally affected, aged from two months to ten years. In 35 patients (87.5%) there was a history of diarrhea which was bloody in25. All were treated with peritoneal dial...
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BACKGROUND Hemolytic uremic syndrome is a common cause of acute kidney injury in children. In children, hemolytic uremic syndrome is most commonly associated with gastrointestinal infections caused by Shiga toxin-producing Escherichia coli or other enteric organisms. Although less common, atypical hemolytic uremic syndrome is triggered by multiple factors and portends a significantly worse prog...
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